Frontier Research Institute for Interdisciplinary Sciences
Tohoku University

Topics

Dr. Kusuyama’s review about benefits of parental exercise on offspring health has been published in Nature Metabolism.

2020.09.15

Assistant professor Joji Kusuyama at FRIS, Tohoku University, and Professor Laurie J Goodyear at Joslin Diabetes Center, Harvard Medical School review the effects of maternal and paternal exercise on offspring metabolic health in adulthood, the time of life when metabolic diseases typically surface. Their review has published in Nature Metabolism on September 14th, 2020.
 
Maternal and paternal obesity and type 2 diabetes are recognized risk factors for the development of metabolic dysfunction in offspring, even when the offspring follow a healthful lifestyle. Multiple studies have demonstrated that regular physical activity in mothers and fathers has striking beneficial effects on offspring health, including preventing the development of metabolic disease in rodent offspring as they age. Dr. Kusuyama’s research focuses on the prevention of metabolic dysfunction and congenital diseases in the next generation. This review explains the benefits of maternal and paternal exercise in combating the development of metabolic dysfunction in adult offspring, focusing on offspring glucose homeostasis and adaptations to metabolic tissues. They discuss recent findings regarding the roles of the placenta and sperm in mediating the effects of parental exercise on offspring metabolic health, as well as the mechanisms hypothesized to underlie these beneficial changes.
 
Publication details:
Joji Kusuyama, Ana Barbara Alves-Wagner, Nathan S. Makarewicz, Laurie J. Goodyear,
“Effects of maternal and paternal exercise on offspring metabolism”,
Nature Metabolism 2020.
DOI: 10.1038/s42255-020-00274-7
https://www.nature.com/articles/s42255-020-00274-7
SharedIt: https://rdcu.be/b7bC6
PAGE TOP