Frontier Research Institute for Interdisciplinary Sciences
Tohoku University

Researcher

GUO Yuanyuan

Associate professorDevice and Technology

Mentor Information
Professor
OSUMI Noriko (Graduate School of Medicine)
Research Fields Bioelectronics, Neuroengineering
Research Subjects
  • Advancing multifunctional fibers for reading and controlling biological signals towards future medicine and neuroscience
Academic Society Membership The Japan Society of Applied Physics (JSAP), The Japan Neuroscience Society (JNS), The Electrochemical Society of Japan (ECSJ), The Chemical Sensors Society of Japan, International Society of Electrochemistry (ISE)
Research Outline  

Our research is situated at the intersection of life sciences, medicine, and engineering, with a dedicated focus on unraveling the complexities of neurological and psychiatric disorders, which are major societal challenges. Our team specializes in the research and development of microelectronic fiber technology that enables simultaneous measurement and manipulation of diverse signals across in vitro, in vivo, and wearable settings. Leveraging a thermal drawing technique similar to the process used to make “Kintaro candy”, our approach facilitates the integration of multiple functionalities—such as optical waveguides, electrodes, microfluidic channels, biosensors, and actuators—into a single, soft and flexible fiber. The multifunctional fibers we develop are instrumental not only in foundational research on neurological and psychiatric disorders but also in advancing new diagnostic and therapeutic tools in healthcare and medical treatments.

Our key research areas include:

  • Fiber-based in vivo chemical sensing and imaging
  • 4D actuation fibers that function dynamically across time and space
  • AI-enhanced smart fibers and textiles for studying brain-body interactions

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